For the study, researchers at Guangzhou Medical University in China examined the effects of a synthetic cannabinoid (WIN55, 212-2) on “the proliferation, invasion and migration of SMMC-7721 hepatocellular carcinoma cells and its underlying mechanisms”. Carcinoma is a type of cancer that develops from epithelial cells.
The researchers found that the synthetic cannabinoid (designed to mimic the effects of cannabis-based cannabinoids) can “inhibit the proliferation of SMMC-7721 cells and induce cell apoptosis.” Apoptosis is a process of programmed cell death.
The study notes that cannabinoids “can inhibit the invasion and migration of SMMC-7721 cells through down-regulating the protein expression of MMP-14 [a human enzyme].”
The full study can be found by clicking here.
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