Study: Cannabis Terpenes have “Anti-Inflammatory, Antioxidant, Analgesic, Anticonvulsive, Antidepressant, Anxiolytic, Anticancer, Antitumor, Neuroprotective, Anti-Mutagenic, Anti-Allergic, Antibiotic and Anti-Diabetic Attributes”

A new study has found that cannabis terpenes have attributes that are “anti-inflammatory, antioxidant, analgesic, anticonvulsive, antidepressant, anxiolytic, anticancer, antitumor, neuroprotective, anti-mutagenic, anti-allergic, antibiotic and anti-diabetic”.

The study was published by the European Journal of Medicinal Chemistry. It’s abstract starts by stating that “Cannabaceae plants Cannabis sativa L. and Humulus lupulus L. are rich in terpenes – both are typically comprised of terpenes as up to 3-5% of the dry-mass of the female inflorescence.” Some terpenes “are relatively well known for their potential in biomedicine and have been used in traditional medicine for centuries, while others are yet to be studied in detail.”

With that in mind, “The current, comprehensive review presents terpenes found in cannabis and hops.” They found that “Terpenes’ medicinal properties are supported by numerous in vitro, animal and clinical trials and show anti-inflammatory, antioxidant, analgesic, anticonvulsive, antidepressant, anxiolytic, anticancer, antitumor, neuroprotective, anti-mutagenic, anti-allergic, antibiotic and anti-diabetic attributes, among others.”

Researchers state that “Because of the very low toxicity, these terpenes are already widely used as food additives and in cosmetic products. Thus, they have been proven safe and well-tolerated.”

More information on this study can be found by clicking here.

The post Study: Cannabis Terpenes have “Anti-Inflammatory, Antioxidant, Analgesic, Anticonvulsive, Antidepressant, Anxiolytic, Anticancer, Antitumor, Neuroprotective, Anti-Mutagenic, Anti-Allergic, Antibiotic and Anti-Diabetic Attributes” appeared first on TheJointBlog.

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Study: Cannabis Can Help Treat Schizophrenia, Offering “a Fresh Start and Newfound Hope”

According to a new study published by the open access journal Medicines, and published online by the National Institute of Health, cannabis “can be used as a treatment for schizophrenia… offering a fresh start and newfound hope”.

According to the study’s abstract, “Approximately 0.5% of the population is diagnosed with some form of schizophrenia, under the prevailing view that the pathology is best treated using pharmaceutical medications that act on monoamine receptors.” For the study, researchers reviewed “evidence on the impact of environmental forces, particularly the effect of autoimmune activity, in the expression of schizophrenic profiles and the role of Cannabis therapy for regulating immunological functioning.”

“A review of the literature shows that phytocannabinoid consumption may be a safe and effective treatment option for schizophrenia as a primary or adjunctive therapy”, states the study. “Emerging research suggests that Cannabis can be used as a treatment for schizophrenia within a broader etiological perspective that focuses on environmental, autoimmune, and neuroinflammatory causes of the disorder, offering a fresh start and newfound hope for those suffering from this debilitating and poorly understood disease.”

The study was conducted at the University of New Mexico, with researchers from both the Department of Psychology and the Department of Economics.

The full study can be found by clicking here.

The post Study: Cannabis Can Help Treat Schizophrenia, Offering “a Fresh Start and Newfound Hope” appeared first on TheJointBlog.

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It’s Official: North Dakota Marijuana Legalization Initiative Placed on November Ballot

An initiative to legalize marijuana in North Dakota has officially qualified for the November general election ballot.

According to the North Dakota secretary of state’s office, Legalize ND submitted more than the 13,500 valid signatures required to place their marijuana legalization initiative on the November 6 ballot.

The proposal, if passed, would give North Dakota one of the least restrictive legalization laws in the country. It would allow those 21 and older to possess, cultivate and distribute marijuana for recreational purposes. The initiative would legalize all forms of marijuana, including oils and hash,

In addition, the initiative establishes a 3-step system for marijuana expungements:

  • Step 1.) The state begins to analyze all those currently in prison with charges that would be applicable under the law and flags them for expungment.
  • Step 2.) 30 days after their release from prison, the state shall automatically expunge their records.
  • Step 3.) The state then has 10 additional days to send via certified mail notification of such an event occurring.

If that state fails to expunge a record that qualifies, the person has a right to a court appeal. If the person wins the court appeal, they can sue the state for fiscal damages with the state waiving it’s sovereign immunity in the case.

For more information on Legalize ND’s initiative, click here.

The post It’s Official: North Dakota Marijuana Legalization Initiative Placed on November Ballot appeared first on TheJointBlog.

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Study: Legalizing Medical Marijuana Associated with a 33.7% Reduction in Workplace Fatalities Among Those Aged 25 to 44

According to a new study published by the International Journal of Drug Policy, the legalization of medical marijuana is associated with a large decrease in workplace fatalities .

According to its abstract, the aim of the study “was to determine the association between legalizing medical marijuana and workplace fatalities.” Using data from all 50 states and the District of Columbia between 1992 and 2015 (obtained from the Bureau of Labor Statistics), regression models were adjusted for state demographics, the unemployment rate, state fixed effects, and year fixed effects.

“Legalizing medical marijuana was associated with a 19.5% reduction in the expected number of workplace fatalities among workers aged 25–44”, states the study. This associated “grew stronger over time”, rising to a 33.7% reduction five years after medical marijuana legalization took effect.

Researchers found that medical marijuana laws “that listed pain as a qualifying condition or allowed collective cultivation were associated with larger reductions in fatalities among workers aged 25–44 than those that did not.”

The association between legalizing medical marijuana and workplace fatalities among workers aged 16–24, “although negative, was not statistically significant at conventional levels.”

The study concludes by stating that :The results provide evidence that legalizing medical marijuana improved workplace safety for workers aged 25–44. Further investigation is required to determine whether this result is attributable to reductions in the consumption of alcohol and other substances that impair cognitive function, memory, and motor skills.

The full study can be found by clicking here.

The post Study: Legalizing Medical Marijuana Associated with a 33.7% Reduction in Workplace Fatalities Among Those Aged 25 to 44 appeared first on TheJointBlog.

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Marijuana Expected to be Rescheduled Federally by the Fall

Recently the United States Food and Drug Administration (FDA), for the first time ever, gave approval to a marijuana-based medicine. The company behind the medicine now says he expects the government to reschedule cannabis within 90 days.

“We expect to make Epidiolex available to U.S. patients this fall, following rescheduling which is expected to occur within 90 days of FDA approval,” said GW Pharmarceuticals’ CEO Justin Grover in a recent earnings call. “We have been building commercial inventory in recent months and are in a position to ship product into the U.S. supply chain, once rescheduling is complete.”

In June, Epidiolex became the first marijuana-derived medicine to ever be approved by the FDA. According to Grover, roughly 1,200 people in other countries are currently receiving Epidiolex, mostly for Lennox-Gastraut and Dravet Syndromes.

If rescheduling really does occur within 90 days of the FDA’s approval of Epidiolex, the change should happen by the end of September. The most likely scenario is that marijuana will be shifted to schedule 2, which means it’s still highly regulated but does have some medical value. Another possibility is that marijuana-derived CBD is rescheduled rather than marijuana as a whole, which would be a positive development, but less so.

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Study: CBD Helps Heal Wounds During Their Early Stages

A new study published in the jounal Phytotherapy Research has found that CBD exerts “an antiinflammatory effect in early phase of wound healing process”.

“The effects of cannabidiol (CBD), the main non-psychotropic component of Cannabis sativa, were assessed on oral wound healing in an in vivo model”, states the abstract of the study, which was epublished ahead of print by the U.S. National Institute of Health. “Standardized ulcers” were induced in 60 rats, who subsequently received “intraperitoneal injections of CBD at doses of 0 (control), 5, and 10 mg/kg daily.” Animals were weighed daily, and wound healing was clinically and histologically evaluated after 3 and 7 days of treatment.

“CBD treatment did not influence the wound area of ulcerative lesions at either observation time”, states researchers. “”Conversely, microscopic findings revealed that at Day 3 postwounding, CBD-treated lesions exhibited significantly lower inflammatory scores than those in the control group.” However, “this difference was not observed at Day 7.”

Researchers conclude by stating that “Collectively, these findings indicate that CBD exert an antiinflammatory effect in early phase of wound healing process although it was not sufficient promote clinical improvement of oral traumatic ulcerative lesions.

The full study, conducted by researchers at Pontifical Catholic University of Rio Grande and the University of São Paulo, can be found by clicking here.

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Nearly $600 million in Legal Marijuana Sold in Denver Last Year, $44 Million in Taxes Garnered

There was almost $600 million in marijuana and marijuana products sold in Denver in 2017, resulting in tens of million of dollars in taxes for the city.

According to a new report titled The Denver Collaborative Approach: Leading The Way In Municipal Marijuana Management 2018. there was roughly $587 million in legal marijuana sold throughout Denver in 2017, a 29% increase from the year prior. $377 million of this came from recreational marijuana sales, with the remaining $210 million from the legal distribution of medical marijuana

These sales resulted in around $44 million in taxes. This marks a 20% increase from the marijuana tax revenue the city garnered in 2016.

“This new report demonstrates Denver’s coordinated approach between multiple agencies to manage marijuana is working,” said Denver’s Mayor Michael B. Hancock in a press release sent out earlier today. “We took on the daunting challenge of becoming the first major city in America to manage legalized recreational marijuana and we are having success. That’s because of coordination between Denver’s Excise and Licenses, Denver’s Fire Department, Police Department, Department of Public Health and Environment, Community Planning and Development, as well as our partners in other city agencies, the community from the marijuana industry and public health advocates.”

In Denver, marijuana has been legal since 2013, with the first legal sales taking place in January of the following year.

Denver is the most populated city in Colorado with around 690,000 residents.

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FBI, DEA orchestrate massive raid of suspected illegal marijuana grow operations across Denver metro area

Drug Enforcement Administration and FBI agents joined state and local agencies in a massive, coordinated raid of more than a dozen suspected illegal marijuana growing operations across the Denver metro area Thursday morning, federal officials say.

The post FBI, DEA orchestrate massive raid of suspected illegal marijuana grow operations across Denver metro area appeared first on The Cannabist.

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Study: 80% of Autistic Children Saw Improvements Afer Consuming CBD

In a new study published by the journal Neurology, 80% of children with autism saw improvements in their condition after being administered cannabidiol (CBD).

For the study, 60 children with an average age of 12 were given cannabis oil containing 20% CBD and 1% THC, for a period of seven months.

After the seven-month period, children filled out a questionnaire asking if they noticed any changes in their condition. Parents were asked if they noticed any changes in their child’s condition, and were asked about any changes in their child’s anxiety levels and communication abilities.

According to the study’s lead Dr. Adi Aran, director of the pediatric neurology unit at Shaare Zedek Hospital in Jerusalem, 80% of parents reported a decrease in problematic behavior following the use of CBD, and 62% reported that their child’s behavior improved significantly. Around half of the children claimed they noticed improvements in their communication, and 40% saw significant improvements in their anxiety symptoms.

“According to the astonishing report, eighty percent of the children reported improved functioning!”, says Nachshol Cohen, Founder of Cannabium. “We hope that this research will help to bring about a conceptual change by regulators and policymakers, which will lead to a scientific momentum that will unequivocally demonstrate the positive effects of cannabis on a variety of health problems.”

The study also found that half of the children who participated in the study also reported an improvement in their level of communication, with 40% saying that their anxiety symptoms had significantly improved. A third of the participants did not show symptoms of anxiety before the study began.

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